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MULTI CELLULAR ORGANISMS are so large they can usually be seen with the naked eye.

SINGLE-CELL ORGANISMS tend to be at least 10 times larger than bacteria, or about.

They are single-cell organisms that reproduce independently.

BACTERIA vary widely in size and shape, but tend to be at least 10 times larger than viruses, or at least 1 micrometer (1 millionth of a meter) long.They have so few genes and proteins of their own that in order to reproduce they need to commandeer the machinery of the cells they invade.

VIRUSES are the smallest of all infectious agents, averaging about 100 nanometers (100 billionths of a meter) in length.

The approximate sizes of microbes can be approximated by using the following rule of thumb: